8/22/2023 0 Comments Teletext holidays uk![]() We are currently working with the company to support all their existing customers.” Gary Lewis, chief executive of the Travel Network Group, said: “We can confirm that Truly Travel and Alpha Holidays are no longer members of Travel Trust Association. UK Civil Aviation Authority October 29, 2021 Truly Travel Ltd (trading as Teletext Holidays) no longer holds an ATOL licence.Ĭonsumers impacted by this news should seek support from the Travel Trust Association: The company, which as of October 19 owed £1.2 million in refunds and had paid back £10.8 million since Covid struck, says it is ‘disappointed’ in the regulator’s legal action. Truly Travel’s Teletext Holidays brand is subject to legal action from the Competition and Markets Authority (CMA) over parent company Truly Holdings’ failure to pay refunds on cancelled package holidays. The move comes after the September 2021 Atol renewal process, which enabled Truly Travel’s bookings to be re-contracted. Truly Travel no longer holds an Atol licence, the Civil Aviation Authority confirmed. The TTA, part of The Travel Network Group, will look after and fulfil the firms’ Atol-protected bookings through TTA Travel. To get the latest email updates from the Manchester Evening News, click here.The Travel Trust Association (TAA) has announced that Teletext Holidays parent Truly Travel Ltd, and Alpha Holidays Ltd (trading as ) have left the group having had their membership closed. The travel sector has been one of the hardest hit during the pandemic and has faced the most scrutiny from the watchdog, which wrote to more than 100 firms reminding them of their responsibility to process all refunds within 14 days by law for any cancellations. “The company continues to urge customers who are due a refund under the Package Travel Regulations but have not received it, to contact us directly from their registered email address (which was used to make their booking) on with their booking reference number If we need more information, we will request it.”Īgreements from LoveHolidays,, Virgin Holidays and Tui UK were previously secured by the CMA after thousands of customers complained that the companies had failed to refund them for cancelled trips. “We have engaged in constructive dialogue with the CMA and continue to vigorously pursue any strategy agreed with the CMA. “As at 11th October 2021, we owe £1.2m towards historic and ongoing cancellations and have refunded over £10.8 million. ![]() The CMA said that its actions to date have resulted in Truly Holidays paying more than £7m owed to package holiday customers.Ī spokesperson for Teletext Holidays said: “The company is working as hard as it can and continues to process the remaining refunds due under the Package Travel Regulations to our remaining customers, and as such is very disappointed by the latest action by the CMA. “After engaging with Teletext Holidays extensively, we are now requesting a court order to make sure that the company immediately pays back the money it still owes to customers and refunds people within 14 days going forward.” READ MORE: Sainsbury's has banned the sale of a popular item following calls from dog ownersĬMA chief executive Andrea Coscelli said: “Companies must abide by consumer protection law and treat their customers fairly. In May Teletext Holidays’ parent company, Truly Holidays, and sister company formally agreed to address failures to issue refunds on time.īut the CMA believes that the company needs to do more to tackle the problem. ![]() The Competition and Markets Authority (CMA) announced that it has filed proceedings requesting a court order that package holiday customers with outstanding refunds are repaid immediately, and that those who are entitled to a refund in the future are paid within the 14 days required by law. Teletext Holidays are facing court action from the competition watchdog over delays in refunding consumers for trips cancelled by the coronavirus pandemic. ![]()
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8/22/2023 0 Comments Rss reader firefox addon![]() ![]() Hello and welcome to the Release Management team's blog for all things related to shipping Mozilla products. Follow to keep up with his latest updates. His current focus is on Mozilla's efforts to champion more trustworthy AI in the tech industry. Mark Surman is Executive Director of Mozilla, a global nonprofit that does everything from making Firefox to standing up for issues like online privac. tors be better connected and better informed of any relevant developments. In particular, we want to help non-employee contribu. The primary purpose of this blog is to help communication across and around the Mozilla Gfx team. your browsing experience by adding new features to Firefox, enhancing your interactions with Web content, and changing the way your browser looks. This Firefox Add-ons Blog will help you modify & personalize. + Follow RSSĪ Mozilla's official site for discovering and installing add-ons for the Firefox browser. Firefox Add-ons Blog RSS FeedĪ/blog/feed. h-performance mixed reality to the open Web. Mozilla MR team's goal is to help bring hig. We are bringing high-performance mixed reality to the open Web. ![]() The MDN Web Docs provides information about Open Web technologies including HTML, CSS, and APIs for both web sites and progressive web apps. It is a local (rather than browser or web-based) email application that is powerful yet easy-to-use. Mozilla Thunderbird is a free, open-source, cross-platform application for managing email, news feeds, chat, and news groups. An Internet that truly puts people first, where individuals can shape their own experience and are empowered, safe and independent. Our mission is to ensure the Internet is a global public resource, open an. ![]() Mozilla makes browsers, apps, code and tools that put people before profit. AskVG is a popular website that covers Windows tips, tweaks, troubleshooting and customization. You'll also find the latest updates about Nightly builds of the Firefox web browser here. vides regular latest version updates and news whenever new versions are released for Firefox. This category contains a list of useful tips-n-tricks, troubleshooting, and how-to guides about the Mozilla Firefox web browser. ![]() AskVG » Mozilla Firefox RSS FeedĪ/category/mozilla-f. Windows Report is an independent online publication that covers Microsoft's Windows platform along with its many related products & services. Here we cover Firefox - Mozilla's browser that is always trying to reinvent itself with newer and. + Follow RSSĪ complete guide on discovering Firefox web browser. s, tips, and provides answers to your tech questions. How-To Geek is an online technology magazine that explains technology with article. + Follow RSSįeatures articles that have to do exclusively with Mozilla Firefox. t Mozilla, we work to ensure the internet remains a public resource that is open and accessible to all. Mozilla's blog features guides to making your online life better, stories from the movement, and critical analysis of issues around internet health. a stable point of information about what happens on Nightly, what features or core technologies landed, how Nightly users can help Mozilla fix bugs and regressions and more generally how a tech-savvy person can move from being a consumer of Firefox to a contributor of Firefox. Firefox Nightly News RSS Feedī/feed + Follow RSSįirefox Nightly is the earliest development stage of Firefox, rebuilt every night from the latest code produced by Mozilla. am and feature hundreds of posts from Mozilla. Hacks are produced by Mozilla's Developer Relations te. Mozilla Hacks is written for web developers, designers and everyone who builds for the Web. Get the latest news and updates about Mozilla from the Mozilla community. ibutors and developers working to innovate on your behalf. It is a global community of users, contr. Mozilla is a proudly non-profit organization dedicated to keeping the power of the Web in people's hands. The Mozilla Blog | Dispatches from the Internet frontier. ![]() 8/22/2023 0 Comments Lingo live complaints![]() However, it’s not impossible to learn with either one and what’s better will ultimately be up to the individual student. Duolingo has made a lot of changes to make it easier for “casual” learners and has sacrificed some of the material that actually helps a student retain the material. However, someone who has trouble staying with a difficult task may find that Duolingo is easier and therefore, better for them. LingoDeer’s method of learning reinforces the student’s memory better and makes them more likely to retain what they have learned. (Words deliberately mispronounced were deemed correct, and vice versa.) However, for a tonal language like Mandarin, this is an extremely useful feature, although it’s not without some minor bugs. Unfortunately, this option doesn’t appear to be available for the remaining languages. For students of Mandarin, LingoDeer’s algorithm can determine whether a student’s pronunciation is on point or off the mark. While Duolingo is better for dabblers and beginners, Lingodeer is the better option for people with set goals. LingoDeer Vs Duolingo: Which One Is Better For Beginners? If you have reached your daily goal trumpets sound. You are able to redo certain exercises or to strengthen the skills you already learned -> this helps to reinforce what you have learnedĭuolingo is set up like a game (as described above). Grammar rules are explained in almost every task. If you are unsure about a word in a translation task you can retrieve its meaning/translation. Sometimes the language and the example sentences are unusual and would not be the kind of language you use in reality. There are also recording exercises to improve your speaking skills Phrases or vocabulary you learn are always spoken out loudly. If you want to learn a certain topic, you haven`t got any access to it unless you go through all the previous tasks The operation is very easy and you have a clear overview of the content and different options There is no information in the beginning about how the whole course works There are a lot of images and symbols which actually have the same effect and help to remember what you have learned Offers 95 different language courses in 38 languages LingoDeer Vs Duolingo: Pros And Cons For Each One LingoDeer If you want to learn Khmer, Cantonese, Tagalog, or other less popular languages, unfortunately, you cannot learn with either LingoDeer or Duolingo. So, if you want to learn a language that LingoDeer doesn’t offer, Duolingo is clearly the better choice. ![]() For example, Hungarian, Navajo, and Finnish are currently being developed. Also, Duolingo is constantly adding new language courses. On Duolingo, you can also learn Esperanto, Klingon, and High Valyrian, which are not technically real languages. On Duolingo, you can learn all of the languages listed above, plus: For starters, Duolingo has a much larger selection of languages you can learn. In this category, I think Duolingo is better. LingoDeer Vs Duolingo: Languages You Can Learn However, there are other options like LingoDeer available on the market. ![]() When it comes to language learning apps, almost everyone has heard of Duolingo. ![]() 8/22/2023 0 Comments Netflix stock price jan 1 2019![]() ![]() Mutual Funds & ETFs: All of the mutual fund and ETF information contained in this display, with the exception of the current price and price history, was supplied by Lipper, A Refinitiv Company, subject to the following: Copyright 2019© Refinitiv. Data may be intentionally delayed pursuant to supplier requirements. FactSet (a) does not make any express or implied warranties of any kind regarding the data, including, without limitation, any warranty of merchantability or fitness for a particular purpose or use and (b) shall not be liable for any errors, incompleteness, interruption or delay, action taken in reliance on any data, or for any damages resulting therefrom. Source: FactSetĭata are provided 'as is' for informational purposes only and are not intended for trading purposes. Change value during other periods is calculated as the difference between the last trade and the most recent settle. Change value during the period between open outcry settle and the commencement of the next day's trading is calculated as the difference between the last trade and the prior day's settle. Sources: FactSet, Tullett PrebonĬommodities & Futures: Futures prices are delayed at least 10 minutes as per exchange requirements. ![]() Sources: FactSet, Tullett PrebonĬurrencies: Currency quotes are updated in real-time. Sources: FactSet, Dow Jonesīonds: Bond quotes are updated in real-time. Sources: FactSet, Dow JonesĮTF Movers: Includes ETFs & ETNs with volume of at least 50,000. Stock Movers: Gainers, decliners and most actives market activity tables are a combination of NYSE, Nasdaq, NYSE American and NYSE Arca listings. Overview page represent trading in all U.S. ![]() Indexes: Index quotes may be real-time or delayed as per exchange requirements refer to time stamps for information on any delays. Copyright 2019© FactSet Research Systems Inc. Fundamental company data and analyst estimates provided by FactSet. International stock quotes are delayed as per exchange requirements. stock quotes reflect trades reported through Nasdaq only comprehensive quotes and volume reflect trading in all markets and are delayed at least 15 minutes. ![]() 8/22/2023 0 Comments Download itsycal![]() ![]() It's just very odd that I don't have this problem with literally anything else I use. menu bar icons to choose from: date in calendar, date with border (like Itsycal), static clock, none. Itsycal 0.12.4 ( download diretto) è l’ultima versione della preziosa utility gratuita che aggiunge un calendario direttamente nella barra dei menu del Finder. The only error message I get is: " The application. However, seeing as I'm no longer the only one to have encountered this issue, it may be happening to others too. Download on the App Store Available on Setapp. After updating to Itsycal 11.14, the application no longer works for me. It is definitely changing the file contents too, as the ones downloaded from FIrefox actually run and install correctly.Įither way, it's clear now that the issue is outside of Itsycal. I can't understand why the files would differ at all depending on web browser. Once the software connects and downloads a set of files to work on, you can view progress in the BOINC manager as shown here. This also begs the question, why is the way Homebrew is downloading this (presumably uses Curl, but I really don't know) causing this. If you want, it will display your events as a companion to the Mac Calendar app. I deleted the files and downloaded them again from Chrome, and it is the Chrome downloads that checksum to the wrong values. Itsycal - Product Information, Latest Updates, and Reviews 2023 Product Hunt. Click this to bring up a tiny calendar popup. ![]() Launch the application and you’ll see a calendar icon in your menu bar. Drag the application to your Applications folder. It comes in a ZIP file which you can unarchive by clicking. So, I downloaded the files from Firefox and sure enough both checksums I calculate are the one you got. Head to the itsycal homepage and download the application. Do you use Firefox or Chrome? I don't know why, but that idea popped into my head at seeing your checksums being correct. ![]() 8/22/2023 0 Comments Obs speedrun timer![]() ![]() To actually teach it what the content in that keyframe is, so it can adapt. So then you would need to teach this splitting software some manner of heuristics. You would end up having to 'teach' the splitting software which keyframe to look for and whereas this is entirely possible, as I said before - change one thing and the keyframe may simply never even occur anymore or end up being different somehow and not triggering the split. I just don't see how it could ever be made to work reliably across all speedrunners' systems and related hardware. In fact, splitting in general is a very tough subject to touch on as manual splitting is highly inaccurate as well.įor emulators and PC games it would obviously work but for consoles it would indeed be an entirely separate subject to address but I still feel going with visual input to determine the splits is an even less desirable approach than simply manually splitting. Automated splitting is a very tough subject to address either way. You're not going to be able to do that, obviously. ![]() Does anyone have any thoughts on a particular approach to achieving automated splits? Does the API support requesting the raw pixels of a given scene? Is there any documentation on starting a plugin using the API, or on the codebase at large that might help me out? I'm just now starting the browse the source and determine if this is possible. Using that approach, it might be possible to create a plugin that periodically registers the image on an OBS scene and throws an event if it sees that the image is fully black. It's fairly straightforward to register a still image to a fully black image and throw an event if the similarity between the two images is high enough. Most split timings occur right around when a video game fades to black. I think it might be possible to automate the process of logging a split. How to get into Speedrunning - Livesplit Tutorial. The "split" is allows the runner, and anyone watching, to track the runner's progress compared to the world record time (or a personal best time). If you’re new to LiveSplit, you can watch this tutorial video created by Linkus7 and read through the FAQ. Whenever the speed runner gets to a milestone in their game, say beating a boss or acquiring an item, they hit a button that causes the timer program to record a "split". I'd like to develop something that will help speedrunners ( log splits for their world record runs.Ĭurrently, when people are speed running (trying to beat a video game as quickly as possible), they use programs like wsplit or Llanfair to record their progress against a world record time. Note: Installation might be blocked by Windows Defender or your computer’s antivirus. Step 3 Once extraction is done, find the application inside the folder and run it. r/SequenceBreak for glitching help and tutorials.Brand new to OBS, not brand new to development. Step 1 How to Add a Speedrun Timer on Twitch 13 Go to the official website of LiveSplit timer () and download the app. Speedrunning Discord Channel, the largest general speedrunning discord channelĪll Speedruns Tracker for finding speedrun streams Looking for a specific community discord? Check this list. A lua script for OBS that provides a hotkey controlled text timer for timed content (marathons, speedruns, etc.). ![]() Then, right-click on the timer one more time. Third, after adjusting your own LiveSplit timer and adding as many segments as you need with Insert Below click OK. Second, right-click the timer and go to Edit Splits. Need an explanation on anything speedrun? /u/GomezTheDragon has got you covered First, opening the app after downloading LiveSplit from. If you used hksplitmaker, instead click Open Splits > From File and find the split file, then skip to step 5. Check here for marathons that may not be on the sidebar or that are even further out! Resources for NewcomersĬheck out these tips from /u/AnAngryPanda and ZE3Z Right click on it and select Edit Splits. Here is a community-driven list of marathons kept up by Helix and nes. I may update this soon to add color changes. If you want to restart the timer, click 'reset'. Pressing the pause button pauses the timer, pressing the go button unpauses the timer. If you know of an upcoming marathon, please message the moderators! Welcome to speedrun timer Click the 'Start' Button to begin. ![]() Meme Meta World Record Discussion Personal Best Video Production Event Glitch GDQ All Upcoming MarathonsĪn archive of marathon VOD threads can be found here. World Record Discussion Click below to filter out flair Public Mod Logs Submitting Rules Click below to search by flair This guide aims to have you up and running with recording software and a timer for speedruns quick and easy. Note: We heavily recommend immediately turning off comments on your runs, as otherwise comments are unmoderated. Speedrunning is a play-through of a video game performed with the intent of completing a goal as fast as possible. r/speedrun is a subreddit for the speedrunning community. ![]() 8/22/2023 0 Comments Gta 5 new cars![]() ![]() Grand Theft Auto Online is out now for PC, PS4, and Xbox One, with PS5 and Xbox Series X/S versions coming March 15. ![]() Not only is there support up to 4K resolution, a 60fps frame rate, expanded texture and draw distances, but now all new content to supplement both the racing community and for players to explore and try out. In summary, Grand Theft Auto Online for the PS5 and Xbox Series X certainly comes boxed with several neat gameplay features that'll surely interest some of the game's more veteran players. Namely, players of the Sony platform can snag the keys to the Karin S95 for free by simply transferring online save data from the PS4 to PS5. Weaponized Ignus, Warstock - $3,245,000įor gamers who play Grand Theft Auto Online on the PlayStation 5, there is a chance to pick up some of the listed vehicles at a heavily discounted price by looking out for some of Rockstar's offers and challenges.Alongside the controllable vehicles, there are 36 uncontrollable trains and trailers, as well as completely unused vehicles in the game: 25 trailers 2 unused, unobtainable trailers 9 trains Of all vehicles, both used and unused: 46 of these were added as part of a DLC. Imponte Arbiter GT, Southern Autos - $1,580,000 Grand Theft Auto V features 348 separate, controllable vehicles.Coil Cyclone 2, Legendary Motorsport - $2,250,000.Pfister Astron Custom, Legendary Motorsport - $1,720,000.Nevertheless, Grand Theft Auto Online players will have to check out Legendary Motorsport, Warstock, and Southern San Andreas Super Autos to buy any of the following contemporary vehicles: This is because the cars range from a million to three million dollars, which may be too steep for most players. With that said, except for the Karin S95, connoisseurs will need some deep pockets if they desire to collect all the latest vehicular imports. Tagged in-game as "part of Xbox Series X/S" versions (these will appear on the PlayStation 5 too), there are five autos in total that will drop along with the game on March 15. ![]() Now, with the looming release of the next-generation versions of Grand Theft Auto Online, Rockstar is using the monumental occasion as an opportunity to launch some brand-new exclusive rides. RELATED: GTA Online Players Confused Over Hidden Airport Entrance With this making up quite a number of the player base, Rockstar continues to supplement the ever-growing Grand Theft Auto Online racing community by adding brand-new vehicles to the game through updates and expansions. After all, a lot of the more laid-back adventurers in the game want nothing more than to simply cruise around and see what Los Santos has to offer. Fortunately, this rendition of Grand Theft Auto Online is more than just a port, as it comes loaded with all-new features and advancements, including over four new vehicles.įor the uninitiated, in Grand Theft Auto Online players can use in-game currency to buy getups, lavish apartments, and, above all, luxury cars and motorcycles. With no end in sight to when the bubble is going to burst, it should come as no surprise that the game is making the leap to next-generation consoles. It has been over nine years since Grand Theft Auto Online was first released, but it would seem age has not hindered GTA Online from rolling to the top of sales charts, plus crushing record number player counts to this day. ![]() 8/22/2023 0 Comments Catan universe promo codes 2021![]() ![]() You can build the settlement in the middle of an opponent’s road (as long as your own road connects to it and there is at least one gap before any other existing settlements). ![]() What resources do you need to build a settlement in Catan? The game is played with six dice, the faces of which depict one of six resources (brick, lumber, wool, grain, ore, or gold). ![]() Human resource is considered to be the most significant resource of a country, which directly contributes to the countries economy with its productivity. The discarded cards from all players go into a single pile of cards (similar to free parking in the game Monopoly). When a player rolls, any player with eight or more cards must discard half of their Resource Cards. Can you break up longest road with a settlement? The first player to have or more continuous road segments, from one point to another without doubling back, may claim this card.Ĭan you roll a double in Catan? Yes, the player receives the resources from the roll, and gets to roll the dice again in the same turn. The Longest Road is a special card included in Catan and is worth victory points. If the port has a question k with a : symbol, that means you can now trade in of any one resource to get one of any resource you want. If you have a settlement on one of the two spots that touches a port, you have access to that port. Moreover Ore is superior to Wheat because of simple supply and demand. Ore is a valuable late game resource as all players will need it to get their last few victory points. A number of small dice-related adjustments like this one can be made to change up how a Catan game feels.īoth Ore and Wheat have many claims for the title of most valuable resource but in the end Ore trumps wheat. Roll double, roll again It’s another simple change that will speed games up, add a bit of excitement to rolls and give more resources to players over the course of a game. The more you trade, the better your chances of victory. ![]() Leave enough room to expand when placing your first settlements. Do not underestimate the value of harbors. You need both to build roads and settlements. Tips to win Catan Brick and lumber are the most important resources at the beginning of the game. 500 Catan Gold – $4.99 >GET NOW FOR FREEGET NOW FOR FREEGET NOW FOR FREEGET NOW FOR FREEGET NOW FOR FREEGET NOW FOR FREEWith a settlement on this port you can exchange of any one resource for of any resource of your choice from the bank. If you have a settlement on this port it allows you to exchange ore resources for one of any resource from the bank. Are you supposed to show your cards in Catan? You can stash as many as red Suns in your account at the same time. You can earn some of those during the user journey to get you started and via promotions on our social media channels as well as on our Discord server. Make sure to keep count of your victory points (and your opponents’!) throughout the game by keeping track of buildings and any Longest Road/Largest Army bonuses.Ī red Sun is a temporary Sun meaning once you use it is gone. The aim of Catan is simple: the first player to victory points on their turn wins. Again, wheat is most important, this time by less, as wood and ore increase in value as the game goes on. Wheat and ore seem to be most important, while brick and sheep are least important. What is the most valuable resource in Catan?.What is the difference between Catan universe and Catan Classic?.What resources do you need to build a settlement in Catan?.Can you break up longest road with a settlement?.Are you supposed to show your cards in Catan?.How do you get different maps in Catan Universe?. ![]() ![]() ![]() Third, if there is no crosswalk, then as close as practicable to the nearest line of the intersecting roadway. Second, on the near side of the intersection. First, stop signs could be installed by the nearest line of the crosswalk. Moreover, 625 ILCS 5/11-302 regulates in detail where stop signs could be placed. In Illinois, every stop sign shall conform to the State Manual and Specifications. Illinois Law Regulates In Detail the Process of Installation of Stop Signs. Clearly, stop signs are necessary to prevent car accidents, injuries and even deaths at the intersections where the only safe way of crossing requires a full stop and to proceed with caution. Of course, stop signs protect drivers from blind corners obstructed by cars, trees and the like. The main purpose of stop signs is to control the safe flow of traffic through intersections and streets. The Traffic Offense of Disobeying a Stop Sign in Illinois.Īs a matter of fact, there are a lot of stop signs in Illinois. Usually, it is a great benefit for a person when a traffic ticket requires a person to appear in court during a business day. Most often, Stop Sign Ticket Chicago Criminal Defense Attorney will take care of your case without requiring you to go to court. Certainly, you will hire an experienced criminal defense attorney who knows how to handle your situation. Therefore, he will present your Stop Sign Traffic Ticket case in a persuasive way. As a result, Chicago Criminal Defense Attorney Tikhvinskiy knows the law and the court rules. Usually, every day, he helps people who receive traffic tickets in Illinois. Stop Sign Ticket Chicago Criminal Defense Attorney Fights and Wins Stop Sign Traffic Tickets On a Regular Basis!įirst, Stop Sign Ticket Chicago Criminal Defense Attorney Tikhvinskiy focuses on traffic offenses. ![]() ![]() ![]() Our findings can inform epidemiologic models that rely on serosurveys to estimate disease burden. ![]() solium nonendemic area was 2 years for parenchymal disease, 4 years for ventricular disease, and 8 years for subarachnoid disease. Median time to seroreversion after cure in this cohort in a T. Eight years after neurocysticercosis cure, 11.1% of patients with parenchymal, 47.3% with subarachnoid, and 41.7% with ventricular disease were still seropositive. Triplex results were concordant with 98% of positive and 100% of negative enzyme-linked immunoelectrotransfer blots. We used that assay to test sequential serologic responses over several years after neurocysticercosis cure in 46 patients, 9 each with parenchymal or ventricular neurocysticercosis and 28 with subarachnoid disease. ![]() We optimized a triplex serologic ELISA by using synthetic GP50, T24H, and Ts18var3 antigens for T. However, assessments of Taenia solium seropositivity durability in patients with various neurocysticercosis types are lacking. Neurocysticercosis prevalence estimates often are based on serosurveys. Clinician and public awareness of CTS and efforts to prevent transmission are needed. Since the first report of CTS in Curitiba in 2011, sporotrichosis has increased substantially, indicating continuous disease transmission. The main clinical form of sporotrichosis was lymphocutaneous (63%), followed by localized cutaneous (24%), ocular (10%), multisite infections (3%), and cutaneous disseminated (<0.5%). Incidence increased from 0.3 cases/100,000 outpatient visit-years in 2011 to 21.4 cases/100,000 outpatient visit-years in 2021 of the 216 cases, 58% (n = 126) were diagnosed during 2019–2021. Proven sporotrichosis was established in 84 (39%) patients and probable sporotrichosis in 132 (61%). We calculated incidence and mapped geographic distribution of cases in Curitiba, Brazil, by reviewing medical records from 216 sporotrichosis cases diagnosed during 2011–May 2022. We examined and described the emergence of cat-transmitted sporotrichosis (CTS) caused by the fungal pathogen Sporothrix brasiliensis. Zoonotic outbreaks of sporotrichosis are increasing in Brazil. Factors predictive of higher peak values and longer time to seroreversion included increasing age, male sex, higher body mass index, and non-Caucasian race. Within the cohort, only 0.75% of persons became seronegative. The observed peak signal-to-cutoff value varied widely, but the waning rate was consistent across the range, with a half-life of 122 days. We analyzed overall signal-to-cutoff values for 48,330 donations (average 2.5 donations/person) that had an average observation period of 102 days. We longitudinally evaluated a cohort of 19,323 blood donors who had evidence of recent infection by using a widely available serologic test to determine the dynamics of such waning. Antibodies to the nucleocapsid protein of SARS-CoV-2 indicate previous infection but are subject to waning, potentially affecting epidemiologic studies. We evaluated antibodies to the nucleocapsid protein of SARS-CoV-2 in a large cohort of blood donors in the United States who were recently infected with the virus. 18S gene sequencing and amplified length polymorphism analysis revealed distinct clustering of R. homothallicus against the commonly used antifungals (amphotericin B, itraconazole, posaconazole, and isavuconazole ). We also performed antifungal-susceptibility testing, which indicated a low range of MICs for R. 104/266 ) after adjusting for age, intracranial involvement, and surgery. homothallicus infection was independently associated with better survival (odds ratio 0.08 p = 0.001) than for R. homothallicus accounted for 43 (6.8%) of the 631 cases of mucormycosis. homothallicus infection and the 30-day mortality rate in rhino-orbital mucormycosis attributable to R. The objectives were ascertaining the proportion of R. We retrospectively reviewed consecutive cases of mucormycosis reported from a tertiary-care center in India to determine the clinical and mycologic characteristics of emerging Rhizopus homothallicus fungus. ![]() |
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